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Thomas Debray0000-0002-1790-2719

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External validation of clinical prediction models using big datasets from e-health records or IPD meta-analysis: opportunities and challenges.

External validation of clinical prediction models using big datasets from e-health records or IPD meta-analysis: opportunities and challenges

Riley RD, Ensor J, Snell KI, Debray TP, Altman DG, Moons KG, Collins GS

Access to big datasets from e-health records and individual participant data (IPD) meta-analysis is signalling a new advent of external validation studies for clinical prediction models. In this article, the authors illustrate novel opportunities for external validation in big, combined datasets, while drawing attention to methodological challenges and reporting issues.

This article is distributed under the terms of the Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

CC BY 4.0